Firalis Group

Firalis expertise

In-house expertise Biomarker discovery → IP
Assay validation & testing → CE Marking
Regulatory BM qualification → IVD Tools

Firalis Patent portfolio

Cardiovascular Disorders Patent n° Filing date
NGAL - Methods and kits for detecting cardiac remodeling in subjects without clinical signs of heart failure EP2766732B1 21-10-2009
NGAL/MMP-9 Complex - Methods and kits for detecting cardiac remodeling in subjects without clinical signs of heart failure EP2766732B1 12-10-2012
NGAL/MMP-9 Complex for detecting cardiac remodeling in a subject without clinical signs of heart failure US9121858B2 12-10-2012
IF-1 - Method for assessing a subject's risk of having a cardiovascular disease. EP2668507B1 25-01-2012
IF-1 - Method for measuring the level of circulating inhibitory factor 1 protein in a subject US9945871B2 23-04-2015
Biomarkers of identifying myocardially-infarcted patients having an increased risk of developing a heart condition, for levels of VEGF, Thrombospodin-1 and/or Placental Growth Factor (PGF) EP2362942B1 30-10-2009
Cardiac LncRNA for diagnostic, prognostic and therapeutic uses of long noncoding RNAs for pathologies and toxicities inducing heart disorders WO2018229046A1 12-06-2018

PACIFIC - HFpEF

Scientific aim: To redefine HFpEF, a heterogeneous syndrome, by the unbiased and multidimensional identification of principal components allowing a new categorization of patients